What is chronic pain?
Chronic pain is a condition that persists for at least 12 weeks and can last for years. It is characterized by occurring in different areas of the body and can manifest as burning or pain in the affected area. Furthermore, it can be continuous or intermittent, appearing and disappearing for no apparent reason [[1]].
The role of CBD in chronic pain
The endocannabinoid system (ECS) is a cellular signaling system present in all humans. CBD has been found to interact with endocannabinoid receptors in the ECS, which are distributed throughout the body. This interaction can generate analgesic and anti-inflammatory responses, helping to relieve chronic pain [[2]].
Properties of CBD for pain
CBD has been shown to have anti-inflammatory and analgesic properties that can relieve chronic pain. Studies have found that cannabinoids, including CBD, have significant analgesic effects compared to placebo [[3]]. Additionally, CBD may also have antiemetic, neuroprotective, antioxidant, and antipsychotic properties [[4]] [[5]] [[6]].
CBD Side Effects
Although CBD generally does not cause the same side effects as cannabis with THC, it can cause mild adverse reactions such as tiredness, dry mouth, and, in rare cases, diarrhea. Dizziness, changes in appetite, and headaches have also been reported in some cases. However, these side effects are minimal compared to the adverse effects of other medications such as ibuprofen or paracetamol [[7]].
CBD dosage for chronic pain
The ideal dosage of CBD for chronic pain can vary depending on each person’s weight and desired results. In general, studies that have shown improvements in the treatment of chronic pain with CBD have used high doses ranging from 1 to 1.5 mg per kg of body weight [[8]]. For example, if a person weighs 65 kg, a dose of CBD ranging from 65 to 97 mg is recommended. However, in cases of more severe pain, it may be necessary to increase the dose and combine CBD with other therapies [[9]].
Conclusions
CBD may be an effective option for relieving chronic pain due to its analgesic and anti-inflammatory properties. However, it is important to keep in mind that each person is unique and may require personalized dosages and treatment approaches. It is always advisable to consult a healthcare professional before beginning any CBD regimen for chronic pain [[10]].
