Introduction
Personalized medicine with CBD offers a wide range of options for the treatment of various conditions. With the increasing availability of cannabis products on the market, it is important to understand how to use CBD effectively. In this article, we will explore the proper dosages and different routes of administration of CBD to maximize its therapeutic benefits.
The therapeutic potential of cannabis
Cannabis has been used medicinally for centuries and has been shown to have therapeutic properties in the treatment of various conditions. Some of the biomedical benefits of cannabis include stimulating appetite, reducing nausea and muscle spasms, and relieving pain. Furthermore, its use has been suggested in the treatment of diseases such as epilepsy, glaucoma and asthma [[1]].
CBD and other cannabinoids
Cannabis contains more than 100 cannabinoids, including THC and CBD. These compounds interact with each other in our body, which is known as the ‘entourage effect’. CBD and THC interact synergistically, enhancing the healing properties of each other. CBD can enhance the analgesic and anti-cancer properties of THC, while reducing its psychoactivity. Additionally, CBD can mitigate the adverse effects of THC, such as anxiety [[2]] [[5]].
CBD Bioavailability
The bioavailability of CBD refers to the amount of medication that reaches its site of action once administered. The bioavailability of CBD depends on the dose and the form of administration used. There are different ways to take CBD, such as edibles, oral preparations, vaporizers, and topicals, and each has a different bioavailability [[9]].
Routes of administration of CBD
Inhalation is one of the most popular routes of administration for CBD, whether through a traditional cigarette or an e-cigarette. This pathway provides rapid and efficient delivery of cannabinoids to the brain. Other routes of administration include topical application, sublingual administration, and oral administration. Each of these pathways has different onset times, maximum concentration in the blood and duration in the body [[4]] [[11]] [[15]].
Dose titration and dosage of CBD
Dose titration is the process of starting with a low dose of a medication and gradually adjusting it to obtain maximum benefit without adverse effects. In the case of CBD, it is recommended to start with microdoses and gradually increase the dose until the desired therapeutic effect is achieved. CBD dosage varies depending on the condition being treated, and it is important to consult a doctor trained in the use of cannabis for an appropriate dosage recommendation [[14]].
Patient follow-up
It is important to properly monitor the patient using CBD to evaluate the effectiveness of the treatment and make adjustments if necessary. Depending on several factors, such as the patient’s familiarity with cannabis and comorbid medical conditions, follow-up visits may be required every 1 to 6 months. Additionally, it is recommended to keep a record of symptoms and response to cannabis treatment to help the physician determine the most effective dose and route of administration [ [15] ].
Conclusions
Personalized medicine with CBD offers a wide range of therapeutic options for the treatment of various conditions. It is important to understand the proper dosages and different routes of administration of CBD to maximize its benefits. Dose titration and patient monitoring are key aspects to ensure effective and safe treatment. Consulting a doctor trained in the use of cannabis is essential to obtain an appropriate dosage recommendation and make any necessary adjustments based on each patient’s individual needs.
