A hope to combat HIV and hepatitis
A team of brilliant Monash University researchers has unlocked a crucial secret that could change the course of the fight against chronic viral infections such as HIV and hepatitis. They have discovered a previously unknown rogue immune cell that hinders the production of effective antibodies.
The mystery of B cells
B cells, guardians of our immunological memory, have baffled scientists for years. Despite their ability to remember past infections, they often show a poor response to persistent infections. This puzzle has finally been solved by Monash researchers.
A new rogue immune cell
The research team, led by Professor Kim Good-Jacobson and Dr Lucy Cooper, has discovered a new immune memory B cell that arises from chronic viral infections. This rogue cell lacks the ability to produce high levels of antibodies, weakening the immune response.
The right time for intervention
Researchers have identified the optimal time to intervene with therapies such as antiviral and anticancer medications. Early intervention is crucial to prevent the formation of these rogue immune cells, while late intervention is ineffective.
Promising therapeutic targets
This discovery opens up new and exciting therapeutic possibilities. By understanding the nature of this rogue cell and the genes it expresses, scientists can develop targeted therapies that enhance antibody responses and reduce the devastating impact of chronic viral infections on global health.
Ongoing research into long COVID
The research team is exploring the possible presence of this rogue cell in long COVID, a condition that affects some people with a reduced ability to fight the symptoms of COVID infection long after the virus has disappeared. This finding could shed light on the underlying causes of this debilitating condition.
