Introduction to CBD
In 2009, a series of CBD-rich Cannabis varieties were discovered accidentally and unexpectedly in Northern California, the agricultural reserve of Cannabis in America. This region allows certified patients to legally access medicinal Cannabis. This discovery began a large democratic laboratory experiment involving CBD-rich Cannabis therapies. The emergence of CBD-rich oil extracted from the whole plant as a therapeutic option has changed the national conversation about Cannabis [[1]].
CBD and its therapeutic benefits
Cannabidiol or CBD is a non-intoxicating component of the Cannabis plant with enormous therapeutic potential. Although CBD does not produce the psychoactive effects associated with THC, it has captured the attention of scientists, health professionals, and medical marijuana patients. It has been used to treat a wide range of ailments, including chronic pain, cancer, Crohn’s disease, diabetes, rheumatoid arthritis, post-traumatic stress disorder, cardiovascular disease, anxiety, antibiotic-resistant infections, multiple sclerosis, schizophrenia, and more [[2 ]].
CBD and THC: a power couple
Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two key components of Cannabis that work best together. CBD improves the analgesic and anti-cancer properties of THC, while decreasing its psychoactivity. Additionally, CBD can mitigate the adverse effects of THC, such as anxiety and tachycardia. When both compounds are present in sufficient quantities in the same variety of Cannabis or Cannabis extract, CBD will lower the psychoactive threshold of THC, while prolonging its effect. This allows for broader therapeutic use of Cannabis, especially in conditions that may be less responsive to high THC formulations [[3]].
Ways to consume CBD
There are various ways to consume CBD, and the choice depends on individual preferences and needs. CBD-rich Cannabis flower varieties for smoking or vaporizing are available at many medical marijuana dispensaries. However, most patients prefer non-inhalable CBD products, such as Cannabis oil concentrates. These products can be taken sublingually, orally (as edibles, pills, tinctures, and gelcaps), or applied topically. They can also be inhaled through a vaporizer. Each administration method has different onset times and duration of effect [[4]].
CBD and epilepsy
Cannabis has been used for thousands of years as medicine to control seizures. Scientific studies have documented the anticonvulsant effects of CBD, THC, and the entire Cannabis plant. High CBD, low THC strains of Cannabis, as well as oil extracts, have been shown to significantly improve intractable seizures in some children. However, it is important to note that low THC Cannabis oils do not work for all patients. Some children may require a small amount of THC to control their seizures [[5]].
Dosage and recommendations
The optimal dosage of CBD may vary depending on the person and the ailment being treated. It is advisable to start with small doses and gradually increase if necessary. It is important to observe the effects and adjust the dose or CBD:THC ratio as necessary. Additionally, it is essential to consult with a doctor, especially if you are taking other medications, as CBD can interact with certain enzymes and affect the way other compounds are metabolized [[6]].
CBD quality and safety
When choosing CBD-rich products, it is important to look for clear labels that show the amount and ratio of CBD and THC per dose, as well as the manufacturing date and batch number. Additionally, it is recommended to select products made with quality ingredients and that have been tested in laboratories to ensure that they are free of contaminants. It is preferable to avoid products extracted with toxic solvents and opt for safe extraction methods, such as supercritical CO2 or food grade ethanol [[7]].
The future of CBD
CBD has gained popularity in recent years due to its numerous therapeutic benefits. As Cannabis legalization progresses in different countries, it is important to ensure that access to CBD is not monopolized by large pharmaceutical companies. Cannabis is a medicinal plant and should be regulated as such, allowing patients to have access to a wide range of remedies from the whole Cannabis plant, rather than being limited to isolated CBD products [[8]].
