What is CBD?
CBD is a cannabinoid compound that, unlike tetrahydrocannabinol (THC), has distinct and different properties. First discovered in 1940 by Roger Adams and chemically identified in 1963 by Mechoulam and Shvo, CBD is derived from cannabidiol acids (CBDA) present in the hemp plant.
How CBD and CBDA Work in the Body
CBD and CBDA interact with the body’s endogenous system (endocannabinoid system or EC), regulating serotonin and capsaicin receptors, contributing to their positive effects on anxiety, mood, nausea, inflammation and pain.
Important Differences between CBD and CBDA
CBDA is absorbed more effectively than CBD in oral capsule form, and animal studies suggest that CBDA is more potent than CBD in models of seizures, pain, nausea, and anxiety.
Benefits of CBD and CBDA
CBD and CBDA have shown benefits in reducing inflammation, anxiety, pain, sleep quality, neurological system recovery, pain signaling, intestinal function, tissue recovery, and treatment of symptoms of cancer, among others.
Therapeutic Use of CBD and CBDA
CBD and CBDA are used to treat anxiety disorders, improve sleep quality, relieve pain, reduce seizures, and as an adjunct in the treatment of cancer and arthritis.
Legal Considerations
CBD, derived from hemp and with less than 0.3% THC, is legal in all states in the United States, but state and local laws vary regarding its sale, production and use.